The report, from recruitment specialist Reed, says two out of five people regularly hit transport problems on their way to work, missing half a working week per year on average.
A spokesperson for Reed said: 'Britain's transport chaos is beginning to bite deep into our economy. In addition to the quantifiable cost of time lost to business from poor transport links, the additional stress is beginning to take its toll.'
The Midlands are particularly hard hit, although some of the chaos is their own doing - £1.4bn is lost in working time in the area, but 71% of Midlanders drive to work on their own, 12% higher than the UK average.
The survey found 64% of the UK's population drive to work, with 59% doing so on their own.
The spokesperson added: 'Just one in 20 UK workers car share on their journey to work, yet congestion on our roads is the single biggest cause of transport problems. Major investment is needed to ease problems in our transport infrastructure, but drivers could help ease their own short-term problems if more shared cars in the morning.'