The £3.6m scheme involves renewing seven miles of the road surface on the westbound carriageway of the M4 near Baydon.
Work will also take place to strengthen the Membury footbridge and the Breach Copse, Inholmes and Bayfield accommodation bridges.
The new surface will give road users a quieter and smoother journey. The work being carried out on the bridges will enhance safety by improving their protection against impact.
Three lanes will be open in each direction during daytime works and occasional night time (10pm-6am) lane closures will be used as and when required.
For the safety of road users and the workforce, there will be a 50mph speed limit through the works enforced by average speed cameras. A free recovery service will be provided for broken down vehicles.